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Thermo Fusion High resolution mass spectra (up to 500,000) can be obtained using a Thermo Scientific Orbitrap Fusion Tribrid mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Thermo Scientific Vanquish Neo nano-UHPLC system. Modes of fragmentation include CID/HCD/ETD. Data generated in any of the Thermo mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Proteome and Compound Discoverer. |
 | Waters Synapt G2-S HDMS High resolution mass spectra (over 40,000) can be obtained in concert with gas-phase ion mobility separations. Sample introduction may be accomplished via direct infusion or by a Waters nanoACQUITY UPLC system. Data generated in any of the Waters mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Protein Global Lynx Server (PLGS) intended for bottom-up protein analysis. |
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Thermo Q Exactive Focus High resolution mass spectra (up to 70,000) can be obtained using a Thermo Scientific Orbitrap Q Exactive Focus mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Thermo Scientific UltiMate 3000 UHPLC system. Data generated in any of the Thermo mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Proteome and Compound Discoverer. |
 | Agilent 6420 Unit resolution MS and MS/MS spectra can be obtained using an Agilent Technologies 6420 Triple Quad mass spectrometer. Sample introduction may be accomplished via direct infusion or by an Agilent Technologies1260 Infinity HPLC system. |
 | Thermo TSQ Evo 8000 Unit resolution MS and MS/MS spectra can be obtained using a Thermo Scientific TSQ Evo 8000 mass spectrometer. Sample introduction may be accomplished via a Thermo Scientific TriPlus RSH autosampler or a Markes International ULTRA-xr/UNITY-xr autosampler/thermal desorption unit. Samples can be separated after sampling on a Thermo Scientific Trace 1310 gas chromatography system. |
 | Thermo ISQ 7000 Unit resolution MS spectra can be obtained using a Thermo Scientific ISQ 7000 mass spectrometer. Sample introduction may be accomplished via a Thermo Scientific AI 1310 autosampler. Samples can be separated after sampling on a Thermo Scientific Trace 1310 gas chromatography system. |
 | Agilent 7900 Metal analysis can be accomplished using a 7900 Agilent Technologies ICP-MS. Sample introduction may be accomplished via an Agilent Technologies ASX-500 Series autosampler. |
| Buker timsTOF HT The Mass Spectrometry Center is equipped with the state-of-the-art Bruker timsTOF HT mass spectrometer, coupled with the Bruker nanoElute 2 nano-LC system, offering advanced capabilities for high-sensitivity, high-throughput proteomics and metabolomics. The timsTOF HT features trapped ion mobility spectrometry (TIMS) combined with time-of-flight (TOF) detection, enabling fast, accurate, and deep profiling of complex biological samples. Its high-speed PASEF® acquisition method significantly increases sequencing speed and sensitivity without compromising data quality. Paired with the nanoElute 2, the system delivers precise, low-flow chromatographic separation ideal for limited sample amounts. This setup is optimized for both discovery and targeted workflows and is bundled with Bruker's ProteoScape® software, enabling real-time DDA-based protein identification during data acquisition. |
| Bruker Microflex MALDI The Bruker microflex® MALDI-TOF mass spectrometer is a compact and user-friendly system designed for fast and accurate analysis of biomolecules, polymers, and small molecules. It is equipped with a nitrogen laser with a variable repetition rate, allowing flexibility for different sample types. The instrument can be operated in either linear or reflectron mode, offering both routine and high-resolution analysis options in one system. The facility provides 96-spot MALDI target plates to users to support a variety of applications. The system is controlled using the intuitive flexControl™ software for easy data acquisition, and data processing is handled by the flexAnalysis suite, which provides tools for peak identification and result interpretation. |
| Thermo Exploris 480 The Thermo Scientific™ Orbitrap Exploris™ 480 benchtop LC-HRMS mass spectrometer, equipped with the Vanquish™ Neo nano-UHPLC system, offers unparallel mass accuracy, extra speed (up to 40 Hz), robustness and simplicity for both proteomics and small molecule research. With high mass resolution capabilities of up to 480,000 (FWHM) at m/z 200, the instrument enables accurate mass detection and confident identification of complex analytes. Sample introduction can be achieved through direct infusion or via the Vanquish Neo nano-UHPLC, offering high sensitivity and low-flow chromatographic separation. Data generated on the Exploris 480 and other Thermo Scientific mass spectrometers in the center can be processed on a dedicated workstation equipped with Thermo Scientific™ Proteome Discoverer™ and Compound Discoverer™ software for comprehensive qualitative and quantitative analysis. |
| Thermo Exploris 120 The Thermo Scientific™ Orbitrap Exploris™ 120 benchtop LC-HRMS mass spectrometer, equipped with the Vanquish UHPLC system, is designed to deliver operational simplicity, productivity and ruggedness for both proteomics and small molecule research. With high mass resolution capabilities of up to 120,000 (FWHM) at m/z 200, the instrument enables accurate mass detection and confident identification of complex analytes. Sample introduction can be achieved through direct infusion or via the Vanquish Neo nano-UHPLC, offering high sensitivity and high-flow chromatographic separation. Data generated on the Exploris 120 and other Thermo Scientific mass spectrometers in the center can be processed on a dedicated workstation equipped with Thermo Scientific™ Proteome Discoverer™ and Compound Discoverer™ software for comprehensive qualitative and quantitative analysis. |